Anne Sieben Selected Research

Peptides (Polypeptides)

11/2022	Associating Alzheimer's disease pathology with its cerebrospinal fluid biomarkers.
11/2020	Amyloid-β1-43 cerebrospinal fluid levels and the interpretation of APP, PSEN1 and PSEN2 mutations.

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Anne Sieben Research Topics

Disease

16	Alzheimer Disease (Alzheimer's Disease) 10/2023 - 12/2015
9	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 10/2023 - 09/2012
7	Frontotemporal Dementia (Semantic Dementia) 10/2023 - 11/2015
5	Dementia (Dementias) 01/2023 - 07/2017
3	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2021 - 11/2015
2	Tauopathies 07/2022 - 12/2018
2	Primary Progressive Aphasia 01/2022 - 12/2018
2	Parkinson Disease (Parkinson's Disease) 12/2021 - 01/2017
2	Proteostasis Deficiencies 01/2018 - 09/2012
1	Prion Diseases (Transmissible Spongiform Encephalopathies) 09/2023
1	Inflammation (Inflammations) 07/2023
1	Neuroinflammatory Diseases 07/2023
1	Amyloid Plaque 11/2022
1	Mitochondrial Diseases (Mitochondrial Disease) 07/2022
1	Seizures (Absence Seizure) 07/2022
1	Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease) 12/2021
1	Lewy Body Disease (Lewy Body Dementia) 12/2021
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2021
1	Death (Near-Death Experience) 01/2019
1	Chromosome Inversion (Chromosomal Inversion) 01/2019
1	Broca Aphasia (Expressive Aphasia) 12/2018
1	Atrophy 01/2018
1	Cognitive Dysfunction 01/2017
1	Cerebrovascular Disorders (Cerebrovascular Occlusion) 01/2016
1	Neurobehavioral Manifestations 01/2016
1	Disease Susceptibility (Diathesis) 09/2014
1	Sarcoma (Soft Tissue Sarcoma) 09/2012
1	Atherosclerosis 03/2012
1	Neoplasms (Cancer) 03/2012
1	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 09/2009
1	Glioblastoma (Glioblastoma Multiforme) 05/2007
1	Multiple System Atrophy 04/2006

Drug/Important Bio-Agent (IBA)

13	Biomarkers (Surrogate Marker)IBA 01/2023 - 09/2012
6	Proteins (Proteins, Gene)FDA Link 07/2023 - 09/2012
5	DNA-Binding Proteins (DNA Binding Protein)IBA 10/2023 - 09/2012
5	Amyloid (Amyloid Fibrils)IBA 01/2023 - 01/2018
3	ProgranulinsIBA 10/2023 - 11/2015
2	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2023 - 09/2012
2	Peptides (Polypeptides)IBA 11/2022 - 11/2020
1	Prion ProteinsIBA 09/2023
1	Toll-Like Receptor 9IBA 07/2023
1	CytokinesIBA 07/2023
1	Protein AggregatesIBA 07/2023
1	ProteomeIBA 01/2023
1	Protein Isoforms (Isoforms)IBA 01/2023
1	Threonine (L-Threonine)FDA Link 11/2022
1	Amino Acids FDA Link 11/2022
1	tau Proteins (tau Protein)IBA 11/2022
1	NG-Nitroarginine Methyl Ester (L-NAME)IBA 07/2022
1	Nitric Oxide Synthase (NO Synthase)IBA 07/2022
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 07/2022
1	NeurograninIBA 12/2021
1	SynucleinsIBA 12/2021
1	PresenilinsIBA 11/2020
1	Dipeptidyl-Peptidases and Tripeptidyl-PeptidasesIBA 01/2019
1	THK5351IBA 12/2018
1	Neurofilament ProteinsIBA 01/2018
1	sortilinIBA 01/2018
1	GranulinsIBA 01/2018
1	Amyloid beta-PeptidesIBA 01/2018
1	EpitopesIBA 07/2017
1	Nonsense Codon (Nonsense Mutation)IBA 01/2017
1	Neurotransmitter Agents (Neurotransmitter)IBA 01/2016
1	Psychotropic Drugs (Psychoactive Drugs)IBA 01/2016
1	UbiquitinIBA 01/2016
1	Apolipoproteins E (ApoE)IBA 01/2016
1	Cystatin CIBA 01/2016
1	FilaminsIBA 11/2015
1	hyperforinIBA 05/2007
1	Antidepressive Agents (Antidepressants)IBA 05/2007
1	hyperosideIBA 05/2007
1	Desipramine (Pertofrane)FDA LinkGeneric 05/2007

Therapy/Procedure

1	Therapeutics 01/2022
1	Euthanasia (Mercy Killing) 01/2019
1	Palliative Care (Palliative Therapy) 01/2019
1	Radiotherapy 03/2012
1	Transcranial Magnetic Stimulation 09/2009
1	Deep Brain Stimulation 04/2006